Diễn viên
Beverly D'Angelo
Bag Lady (segment "Happy Birthday")
Taylor Negron
Policeman (segment "Happy Birthday")
Dondré Whitfield
Man in Elevator (segment "Happy Birthday")
Christopher Lloyd
Attorney Bum (segment "Happy Birthday")
Caroline Rhea
Monica (segment "Happy Birthday")
Jenica Bergere
Sally (segment "Happy Birthday")
Karen Sillas
Anna (segment "The Other Side")
Paul Rudd
Kenneth (segment "Reaching Normal")
Alan Rosenberg
Frank (segment "Reaching Normal")
Jolene Blalock
Charlie's Wife (wraparound segments)
Scott Lowell
Charlie (wraparound segments)
Helen Mirren
Distinguished Woman (segment "Happy Birthday") (uncredited)
Ken Hudson Campbell
Security Guard (segment "Happy Birthday")
Jean Kasem
Nurse (segment "Happy Birthday")
Joey Lauren Adams
Sarah (segment "Reaching Normal")
Stephen Tobolowsky
Tom (wraparound segments)
David Hyde Pierce
Barney (segment "Happy Birthday")
Sydney Tamiia Poitier
Hannah (segment "Happy Birthday")
Joel Grey
Dr. Mensley (segment "Reaching Normal")
John Goodman
The Dean (segment "Happy Birthday")
Kimiko Gelman
May Lee Ha (segment "Happy Birthday")
Bruce Davison
(segment "The Other Side")
Andie MacDowell
Lisa (segment "Reaching Normal")
Kathleen Wilhoite
Lucy (wraparound segments)
Ellen DeGeneres
Operator (segment "Reaching Normal") (uncredited)
Travis Wester
Chute Boy (segment "Happy Birthday")
Marissa Jaret Winokur
Dean's Secretary (segment "Happy Birthday")
Anthony LaPaglia
Dr. Maas (segment "The Other Side")